Chronic kidney disease (CKD) can affect cats at any age but is more commonly diagnosed in middle-aged and senior cats, typically those over seven years old. There are several reasons that causes CKD, which are:
1. Natural Aging Process:
Unlike dogs, whose kidneys tend to fail due to infections or inherited conditions, CKD in cats is often linked to gradual wear and tear on the kidneys as they age.
2. Low Thirst Drive:
Cats evolved from desert animals and naturally have a low thirst drive. This means they don’t drink as much water as they should, putting extra strain on their kidneys.

3. Protein Metabolism:
Cats require a high-protein diet, but their kidneys have to filter out protein waste. Over time, this can contribute to kidney damage.
4. Genetic Factors:
Some breeds, like Persians, Siamese, and Abyssinians, are more genetically predisposed to kidney disease.
5. Silent Progression:
CKD in cats often goes unnoticed because symptoms—like weight loss, increased thirst, and urination—develop slowly. By the time a cat is diagnosed, the disease is usually in an advanced stage.